Chemistry and Biology of Metals laboratory UMR 5249 CNRS-CEA-UGA - Other news https://www.cbm-lab.fr/en/Pages/BioCat/Theses.aspx en-US https://www.cbm-lab.fr/PublishingImages/min_logo_CBM.jpg Chemistry and Biology of Metals laboratory UMR 5249 CNRS-CEA-UGA - Other news https://www.cbm-lab.fr/en The SUF machinery from Mycobacterium tuberculosis as a new target for anti-tubercular drugs https://www.cbm-lab.fr/en/Pages/Theses/2024/Ingie-Elchennawi.aspx Thesis presented October 10, 2024 by Ingie Elchennawi. PhD defense;BioCat;Fe/S cluster;SUF;tuberculosis;Mycobacterium tuberculosis;SO; Thu, 10 Oct 2024 10:00:00 GMT Characterization of the thioether bonds - containing peptides of Ruminococcus gnavus E1 https://www.cbm-lab.fr/en/Pages/Theses/2023/Lama-Shamseddine.aspx Thesis presented October 13, 2023 by Lama Shamseddine. sactipeptide;Radical SAM;ranthipeptides;antibacterial peptides;PhD defense;Antibiotic Resistance;BioCat;RumC; Fri, 13 Oct 2023 10:00:00 GMT Deciphering the biosynthesis pathway of carbon monoxide dehydrogenase, a key enzyme in the watergas shift reaction https://www.cbm-lab.fr/en/Pages/Theses/2019/Marila-Alfano.aspx Thesis presented October 17, 2019 by Marila Alfano. PhD thesis available as a pdf file. CODH;BioCat;carbon monoxide;PhD defense;BEE;NiFe hydrogenase; Thu, 17 Oct 2019 10:00:00 GMT RumC peptides, a new family of bacteriocins as viable alternative to conventional antibiotics https://www.cbm-lab.fr/en/Pages/Theses/2019/Steve-Chiumento.aspx Thesis presented October 11, 2019 by Steve Chiumento. PhD thesis available as a pdf file. Radical SAM;sactipeptide;BioCat;PhD defense;antibacterial peptides;RumC; Fri, 11 Oct 2019 10:00:00 GMT New inhibitors of quinolinate synthase as potential antibacterial drugs https://www.cbm-lab.fr/en/Pages/Theses/2018/Jaione-Saez-Cabodevilla.aspx Thesis presented December 06, 2018 by Jaione Saez Cabodevilla. PhD thesis available as a pdf file. NadA;BioCat;antibacterial;PhD defense; Thu, 06 Dec 2018 11:00:00 GMT Elucidation of the role of new actors of the Q8 biosynthesis in E. coli and characterization of the protein complex responsible of the Q8 biosynthesis https://www.cbm-lab.fr/en/Pages/Theses/2015/Mahmoud-Hajj-Chehade.aspx Thesis presented 26 October​ 2015 by Mahmoud Hajj Chehade. PhD thesis available as a pdf file. Coenzyme Q;BioCat;PhD defense; Mon, 26 Oct 2015 11:00:00 GMT Modification of macromolecules by radical insertion. Study of the methylthiotransferase RimO and the 4-demethylwyosine synthase TYW1 both belonging to the Radical-SAM superfamily https://www.cbm-lab.fr/en/Pages/Theses/2014/Thibault-Molle.aspx Thesis presented December​ 12, 2014 by Thibault Molle. PhD thesis available as a pdf file. BioCat;Radical SAM;PhD defense;post-transcriptional modifications;post-translational modifications;Fe/S cluster;RimO; Fri, 12 Dec 2014 11:00:00 GMT Structure and mechanism of Quinolinate Synthase: An enzyme with a [4Fe-4S]2+ cluster and an antibacterial target https://www.cbm-lab.fr/en/Pages/Theses/2014/Alice-Chan.aspx Thesis presented December 05, 2014 by Alice Chan. PhD thesis available in Intranet as a pdf file. BioCat;NadA;Quinolinate synthase;metalloenzyme;antibacterial;PhD defense; Fri, 05 Dec 2014 11:00:00 GMT Artificial hydrogenases: New biosynthetic catalysts for hydrogen evolution https://www.cbm-lab.fr/en/Pages/Theses/2013/Marine-Bacchi.aspx Thesis presented on September 24, 2013 by Marine Bacchi. PhD thesis available as a pdf file. BioCat;SolhyCat;hydrogen production;hydrogenase;PhD defense;biomimetic chemistry;binuclear complex;bio-inspired chemistry;artificial enzyme;catalysis; Tue, 24 Sep 2013 10:00:00 GMT Study of the biosynthesis of coenzyme Q6 in the yeast Saccharomyces cerevisiae https://www.cbm-lab.fr/en/Pages/Theses/2012/Mohammad-Ozeir.aspx Thesis presented October 29, 2012 by Mohammad Ozeir. PhD thesis available as a pdf file. Coenzyme Q;BioCat;PhD defense; Mon, 29 Oct 2012 11:00:00 GMT Biological radical sulfur insertion. A study of methylthiotransferases https://www.cbm-lab.fr/en/Pages/Theses/2011/Simon-Arragain.aspx Thesis presented October 07, 2011 by Simon Arragain. PhD thesis available as a pdf file. BioCat;MiaB;Radical SAM;RimO;post-transcriptional modifications;post-translational modifications;Fe/S cluster;PhD defense; Fri, 07 Oct 2011 10:00:00 GMT Role of the axial cysteine ligand in the iron active site of superoxide reductase https://www.cbm-lab.fr/en/Pages/Theses/2009/Emilie-Tremey.aspx Thesis presented December 03, 2009 by Émilie Tremey. PhD thesis available as a pdf file. SOR;BioCat;PhD defense;superoxide;oxidative stress; Thu, 03 Dec 2009 11:00:00 GMT Superoxide reductase: Mechanism of electron transfer to the active site and the role of lysine 48 in catalysis https://www.cbm-lab.fr/en/Pages/Theses/2009/Florence-Bonnot.aspx Thesis presented November 25, 2009 by Florence Bonnot. PhD thesis available as a pdf file. BioCat;SOR;oxidative stress;superoxide;rubredoxin;PhD defense;hydrogen peroxide; Wed, 25 Nov 2009 11:00:00 GMT Modelling the active site of NiFe hydrogenases: New catalysts for the electro-production of H2 and mechanistic studies https://www.cbm-lab.fr/en/Pages/Theses/2009/Sigolene-Canaguier.aspx Thesis presented on September 24, 2009 by Sigolène Canaguier. PhD thesis available as a pdf file. BioCat;SolhyCat;hydrogen production;electrocatalysis;hydrogenase;PhD defense;binuclear complex;bio-inspired chemistry;ruthenium;NiFe hydrogenase; Thu, 24 Sep 2009 10:00:00 GMT Structural and functional studies of Quinolinate synthase: An iron-sulfur protein as a key target of antibacterial agents https://www.cbm-lab.fr/en/Pages/Theses/2009/Carine-Rousset.aspx Thesis presented May 04, 2009 by Carine Rousset. PhD thesis available as a pdf file. BioCat;NadA;Quinolinate synthase;antibacterial;Fe/S cluster;PhD defense; Mon, 04 May 2009 10:00:00 GMT Study of Spore Photoproduct Lyase, a “Radical-SAM” enzyme involved in DNA repair https://www.cbm-lab.fr/en/Pages/Theses/2008/Alexia-Chandor-Proust.aspx Thesis presented November 28, 2008 by Alexia Chandor-Proust. PhD thesis available as a pdf file. SPL;BioCat;Radical SAM;S-adenosylmethionine;Fe/S cluster;PhD defense; Fri, 28 Nov 2008 11:00:00 GMT Mechanistic studies of iron-sulfur cluster assembly in Escherichia coli: Which role for SufA? https://www.cbm-lab.fr/en/Pages/Theses/2007/Maite-Sendra.aspx Sendra. PhD thesis available as a pdf file. SufA;BioCat;Fe/S cluster;ferredoxin;PhD defense;SO; Thu, 04 Oct 2007 10:00:00 GMT Structural and functional models of the active site of hydrogenase [NiFe]: New bio-inspired catalysts for hydrogen production https://www.cbm-lab.fr/en/Pages/Theses/2006/Yohan-Oudart.aspx Thesis presented on September 28, 2006 by Yohan Oudart. PhD thesis available as a pdf file. BioCat;SolhyCat;hydrogen production;electrocatalysis;hydrogenase;PhD defense;bio-inspired chemistry;ruthenium;NiFe hydrogenase; Thu, 28 Sep 2006 10:00:00 GMT