Artificial Metalloenzymes for Activation of Small Molecules
Published on 25 September 2024
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Mohamed Atta, Olivier Hamelin, Philippe Carpentier
In our group, one theme of research is dedicated to pioneering the development of artificial metalloenzymes designed for the activation of small molecules such as H₂O, N₂, and CO₂. By harnessing the synergy between metal catalysis and protein engineering, we aim to create novel biocatalysts with enhanced reactivity, stability and selectivity for sustainable chemical transformations. This project represents a strong collaboration between our research group and the team of Professor Marc Fontecave at Collège de France, Paris. This partnership brings together complementary expertise and resources, enabling us to tackle these challenges with a multidisciplinary approach. By combining our strengths in protein chemistry, spectroscopy, X-ray structure analysis, and catalytic activities, we are positioned at the forefront of biocatalysis innovation.
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