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UMR 5249 CEA-CNRS-UGA

Welcome to our Website

Published on 29 June 2021
Head of the laboratory
 
Director: Vincent Artero
CEA Research Director
 
Deputy Director: Thierry Rabilloud
CNRS Research Director

Address - Contact
Laboratoire Chimie et Biologie des Métaux
CEA-Grenoble
17 avenue des Martyrs
38 054 Grenoble cedex 09

Secretariat of the laboratory:
Nathalie Chaumery
Tel. : (33) 4 38 78 91 02

Presentation
The LCBM is a federation of cell biologists, protein chemists, synthetic chemists and spectroscopists developing their research in order to provide new insights into the unique question of the physiological function, the structure, the chemical reactivity and the regulation of complex biological systems transporting and utilizing metal ions, and the exploitation of this knowledge to develop bio-inspired systems with similar structures and/or functions.
This is investigated through a great variety of experimental approaches combining molecular and cellular biology of both prokaryotes and eukaryotes, protein chemistry and enzymology, organic and inorganic synthetic chemistry and physico-chemical methods such as spectroscopy and theoretical chemistry. This research results in new concepts and applications in heavy metal toxicology and remediation, in bacterial pathogenicity and antibiotics, in neurodegenerative diseases, in catalysis and biocatalysis for selective transformations of organic compounds and for hydrogen production.

Research thema
Biocatalysis
Physicochemistry of metals in biology
Bioinspired Redox Chemistry
Proteomics for Microbiology, Immunology and Toxicology team
Computational chemistry, Modelling, and X-rays
• Metals and Organs
• Solar fuels, hydrogen and catalysis
Bioenergy & Environment

Metal homeostasis, metalloregulatory proteins and their involvement in bacterial virulence