Head of the laboratory
Address - Contact
Laboratoire Chimie et Biologie des Métaux
CEA-Grenoble
17 avenue des Martyrs
38 054 Grenoble cedex 09
Administrative and Financial Officer
Gabriel BOUTANG Tel. : (33) 4 38 78 13 43
Executive Assistant
Joëlle PAPARELLA Tel. : (33) 4 38 78 91 84
Assistants/Managers
Nathalie CHAUMERY Tel. : (33) 4 38 78 91 02
Claude SENEBIER Tel. : (33) 4 38 78 40 95
Presentation
The LCBM is a federation of cell biologists, protein chemists, synthetic chemists and spectroscopists developing their research in order to provide new insights into the unique question of the physiological function, the structure, the chemical reactivity and the regulation of complex biological systems transporting and utilizing metal ions, and the exploitation of this knowledge to develop bio-inspired systems with similar structures and/or functions.
This is investigated through a great variety of experimental approaches combining molecular and cellular biology of both prokaryotes and eukaryotes, protein chemistry and enzymology, organic and inorganic synthetic chemistry and physico-chemical methods such as spectroscopy and theoretical chemistry. This research results in new concepts and applications in heavy metal toxicology and remediation, in bacterial pathogenicity and antibiotics, in neurodegenerative diseases, in catalysis and biocatalysis for selective transformations of organic compounds and for hydrogen production.
Research thema •
Biocatalysis •
Physicochemistry of metals in biology •
Bioinspired Redox Chemistry •
Proteomics for Microbiology, Immunology and Toxicology team •
Computational chemistry, Modelling, and X-rays •
Metals and Organs •
Solar fuels, hydrogen and catalysis •
Bioenergy & Environment •
Metal homeostasis, metalloregulatory proteins and their involvement in bacterial virulence