Isabelle Michaud-Soret & Sandrine Ollagnier de Choudens
The Ferric uptake transcription regulators (Fur) are transcription factors that controls the expression of genes involved in iron homeostasis, oxidative stress and virulence.
Coupling iron homeostasis and iron-sulfur biogenesis could make sense and may open new perspectives. We try to decipher if iron-sulfur center in the Fur proteins from some bacteria such as
E. coli is an artefact or a reality
in cellulo and what are the structural and functional properties of [Fe-S]EcFur.
More information.