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Ergothioneine, a sulfur active small antioxidant

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Published on 17 September 2024

Isabelle Michaud-Soret


Ergothioneine (EGT) is a fascinating small- antioxidant molecule. Only fungi and bacteria are able to produce it, eukaryotes adsorb it through the diets. There is a growing interest in EGT for its potential health benefits and its role in aging, virulence, dementia and preeclampsia. The literature suggests that the primary role of EGT may be more specific than antioxidant, playing a cofactor role in some enzymes. We try to decipher more specific role and target of EGT using biochemical tools.



Ergothioneine at physiological pH

Postdoc: Chloé Aymard (2022-2023)
Financial support: Plan de relance (2022-2023) with the Innoverda Start-up; LabEx GRAL

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