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Engineering superoxide reductase



​By mutating various residues in the iron environment of the superoxide reductase, an enzyme naturally not involved in oxidative reactions, rwe have made this enzyme an oxygenase. This work allowed to develop an original model for studying the oxygen activation and oxidative catalysis mechanisms. These data may lead to the design of novel biocatalysts used in chemical synthesis.

Published on 1 July 2014

Highlight available in French.


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