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Researchers at our Chemistry and Biology of Metals laboratory are developing anti-bacterial inhibitors targeting a global transcriptional regulator, FUR, and determine the involved mechanisms of inhibition. When these inhibitors bind to FUR, they sterically inhibit the DNA accessibility at its binding site on the protein.
Thesis presented January 19, 2012 by Cheickna Cissé. PhD thesis available as a pdf file.
Thesis presented November 27, 2009 by Sylvia Vitale.
Thesis presented March 30, 2005 by Nadia Abed. PhD thesis available in Intranet as a pdf file.
CEA is a French government-funded technological research organisation in four main areas: low-carbon energies, defense and security, information technologies and health technologies. A prominent player in the European Research Area, it is involved in setting up collaborative projects with many partners around the world.