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A new player in the homeostasis of Zinc

​Zinc is involved in certain diseases (neurodegenerative, cancer ...). Researchers from our laboratory have recently shown that an ion channel (TRPC6) facilitates the import of zinc and when the protein is overexpressed, increases the pool size of the metal trapped in internal compartments of the cell. Finally, overexpression of TRPC6 is accompanied by increased expression of proteins related to the actin cytoskeleton, and changes the cellular architecture.

Published on 30 September 2014
Highlight available in French.

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other results obtained on the topic of the cation channels