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Publications



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Published on 5 March 2025
Choi J-H, Nhari A, Charnay T, Chartier B, Bridou L, Micouin G, Maury O, Banyasz A, Erbek S, Grichine A, Martel-Frachet V, Thomas F, Molloy JK and Sénèque O
 Carbazole-based Eu3+ complexes for two-photon microscopy imaging of live cells.
Inorganic Chemistry, 2025, 64(4): 2006-2019.

Malikidogo KP, Charnay T, Ndiaye D, Choi J-H, Bridou L, Chartier B, Erbek S, Micouin G, Banyasz A, Maury O, Martel-Frachet V, Grichine A and Sénèque O
 Efficient cytosolic delivery of luminescent lanthanide bioprobes in live cells for two-photon microscopy.
Chemical Science, 2024, 15(25): 9694-9702.

Malikidogo KP, Pallier A, Szeremeta F, Bonnet CS and Sénèque O
 A phosphorylated zinc finger peptide bearing a gadolinium complex for zinc detection by MRI.
Dalton Transactions, 2023, 52(19): 6260-6266.

Choi J-H, Fremy G, Charnay T, Fayad N, Pécaut J, Erbek S, Hildebrandt N, Martel-Frachet V, Grichine A and Sénèque O
 Luminescent peptide/lanthanide(III) complex conjugates with push–pull antennas: Application to one- and two-photon microscopy imaging.
Inorganic Chemistry, 2022, 61(50): 20674-20689.

Boudehen Y-M, Faucher M, Maréchal X, Miras R, Rech J, Rombouts Y, Sénèque O, Wallat M, Demange P, Bouet J-Y, Saurel O, Catty P, Gutierrez C and Neyrolles O
 Mycobacterial resistance to zinc poisoning requires assembly of P-ATPase-containing membrane metal efflux platforms.
Nature Communications, 2022, 13(1): 4731.

Zuily L, Lahrach N, Fassler R, Genest O, Faller P, Sénèque O, Denis Y, Castanié-Cornet M-P, Genevaux P, Jakob U, Reichmann D, Giudici-Orticoni M-T and Ilbert M
 Copper induces protein aggregation, a toxic process compensated by molecular chaperones.
mBio​​, 2022, 13(2): e03251-21.

Cepeda C, Denisov SA, Boturyn D, McClenaghan ND and Sénèque O
 Ratiometric luminescence detection of copper(I) by a resonant system comprising two antenna / lanthanide pairs.
Inorganic Chemistry, 2021, 60(14): 17426-17434.

Isaac M, Denisov SA, McClenaghan ND and Sénèque O
 Bioinspired luminescent europium-based probe capable of discrimination between Ag+ and Cu+.
Inorganic Chemistry, 2021, 60(14): 10791-10798. 

Falcone E, Gonzalez P, Lorusso L, Sénèque O, Faller P and Raibaut L
A terbium(iii) luminescent ATCUN-based peptide sensor for selective and reversible detection of copper(ii) in biol​ogical media.
Chemical Communications, 2020, 56: 4797-4800

Fremy G, Raibaut L, Cepeda C, Sanson M, Boujut M and Sénèque O
A novel DOTA-like building block with a picolinate arm for the synthesis of lanthanide complex-peptide conjugates with improved luminescence properties.
Journal of Inorganic Biochemistry, 2020, 213: 111257

Chabert V, Lebrun V, Lebrun C, Latour JM and Sénèque O
Model peptide for anti-sigma factor domain HHCC zinc fingers: High reactivity toward 1O2 leads to domain unfolding.
Chemical Science, 2019, 10: 3608–3615

Cepeda C, Raibaut L, Fremy G, Eliseeva SV, Romieu A, Pecaut J, Boturyn D, Petoud S and Sénèque O
Using native chemical ligation for site‐specific synthesis of hetero‐bis‐lanthanide peptide conjugates: Application to ratiometric visible or near‐infrared detection of Zn2+.
Chemistry-A European Journal​​, 2018, 26(59): 13476-13483.
​ ​​Chabert V, Hologne M, Sénèque O, Walker O and Fromm KM
Alpha-helical folding of SilE models upon Ag(His)(Met) motif formation.
Chemical Communications, 2018, 54(74): 10419-10422

Isaac M, Pallier A, Szeremeta F, Bayle PA, Barantin L, Bonnet CS and Sénèque O
MRI and luminescence detection of Zn2+ with a lanthanide complex-zinc finger peptide conjugate.
Chemical Communications (Camb), 2018, 54(53): 7350-7353

Roux A, Isaac M, Chabert V, Denisov SA, McClenaghan ND and Seneque O
Influence of amino acid sequence in a peptidic Cu(+)-responsive luminescent probe inspired by the copper chaperone CusF.
Organic and Biomolecular Chemistry, 2018, 16(31): 5626-5634

 Sénèque O, Rousselot-Pailley P, Pujol A, Boturyn D, Crouzy S, Proux O, Manceau A, Lebrun C and Delangle P
Mercury trithiolate binding (HgS3) to a de novo designed cyclic decapeptide with three preoriented cysteine side chains.
Inorganic Chemistry, 2018, 57(5): 2705-2713

Tebo AG, Pinter TBJ, Garcia-Serres R, Speelman AL, Tard C, Sénèque O, Blondin G, Latour JM, Penner-Hahn J, Lehnert N and Pecoraro VL
Development of a rubredoxin-type center embedded in a de dovo-designed three-helix bundle.
Biochemistry, 2018, 57(16): 2308-2316

 Chabert V, Hologne M, Sénèque O, Crochet A, Walker O and Fromm KM
Model peptide studies of Ag+ binding sites from the silver resistance protein SilE.
Chemical Communications, 2017, 53(45): 6105-6108

Isaac M, Raibaut L, Cepeda C, Roux A, Boturyn D, Eliseeva SV, Petoud S and Sénèque O
Luminescent zinc fingers: Zn-responsive neodymium near-infrared emission in water.
Chemistry-a European Journal, 2017, 23(46): 10992-10996

Raibaut L, Vasseur W, Shimberg GD, Saint-Pierre C, Ravanat JL, Michel SLJ and Sénèque O
Design of a synthetic luminescent probe from a biomolecule binding domain: Selective detection of AU-rich mRNA sequences.
Chemical Science, 2017, 8(2): 1658-1664

Lebrun V, Ravanat JL, Latour JM and Sénèque O
Near diffusion-controlled reaction of a Zn(Cys)4 zinc finger with hypochlorous acid.
Chemical Science, 2016, 7(8): 5508-5516

Isaac M, Denisov SA, Roux A, Imbert D, Jonusauskas G, McClenaghan ND and Sénèque O
Lanthanide luminescence modulation by cation-pi interaction in a bioinspired scaffold: Selective detection of copper(I).
Angewandte Chemie - International Edition, 2015, 54(39): 11453-11456

Jacques A, Lebrun C, Casini A, Kieffer I, Proux O, Latour JM and Sénèque O
Reactivity of Cys4 Zinc finger domains with Gold(III) complexes: Insights into the formation of "gold fingers".
Inorganic Chemistry, 2015, 54(8): 4104-4113

Lebrun V, Tron A, Lebrun C, Latour JM, McClenaghan ND and Sénèque O
Reactivity of a Zn(Cys)2 (His)2 zinc finger with singlet oxygen: Oxidation directed toward cysteines but not histidines.
Chemistry - A European Journal, 2015, 21(40): 14002-14010

Goure E, Avenier F, Dubourdeaux P, Sénèque O, Albrieux F, Lebrun C, Clémancey M, Maldivi P and Latour JM
A diiron(III,IV) imido species very active in nitrene-transfer reactions.
Angewandte Chemie International Edition, 2014, 53(6): 1580-1584

 Jacques A, Latour JM and Sénèque O
Peptide-based FeS4 complexes: The zinc ribbon fold is unsurpassed to stabilize both the FeII and FeIII states.
Dalton Transactions, 2014, 43(10): 3922-3930

 Lebrun V, Tron A, Scarpantonio L, Lebrun C, Ravanat JL, Latour JM, McClenaghan ND and Sénèque O
Efficient oxidation and destabilization of Zn(Cys)4 zinc fingers by singlet oxygen.
Angewandte Chemie-International Edition, 2014, 53(35): 9365-9368

 Jacques A, Clémancey M, Blondin G, Fourmond V, Latour JM and Sénèque O
A cyclic peptide-based redox-active model of rubredoxin.
Chemical Communications (Camb), 2013, 49(28): 2915-2917

Jacques A, Mettra B, Lebrun V, Latour JM and Sénèque O
On the design of zinc-finger models with cyclic peptides bearing a linear tail.
Chemistry–A European Journal, 2013, 19(12): 3921-3931

Isaac M, Latour JM and Sénèque O
Nucleophilic reactivity of Zinc-bound thiolates: Subtle interplay between coordination set and conformational flexibility.
Chemical Science, 2012, 3: 3409-3420

Bourles E, Isaac M, Lebrun C, Latour JM and Sénèque O
Oxidation of Zn(Cys)4 zinc finger peptides by O2 and H2O2: Products, mechanism and kinetics.
Chemistry–A European Journal, 2011, 17(49): 13762-13772

Sénèque O and Latour JM
Coordination properties of zinc finger peptides revisited: Ligand competition studies reveal higher affinities for zinc and cobalt.
Journal of the American Chemical Society, 2010, 132(50): 17760-17774

Bonnet CS, Fries PH, Crouzy S, Sénèque O, Cisnetti F, Boturyn D, Dumy P and Delangle P
A gadolinium-binding cyclodecapeptide with a large high-field relaxivity involving second-sphere water.
Chemistry–A European Journal, 2009, 15(29): 7083-7093

Coquière D, Le Gac S, Darbost U, Sénèque O, Jabin I and Reinaud O
Biomimetic and self-assembled calix[6]arene-based receptors for neutral molecules.
Organic and Biomolecular Chemistry, 2009, 7(12): 2485-500

Sénèque O, Bonnet E, Joumas FL and Latour JM
Cooperative metal binding and helical folding in model peptides of treble-clef zinc fingers.
Chemistry-A European Journal, 2009, 15(19): 4798-4810

Sénèque O, Bourles E, Lebrun V, Bonnet E, Dumy P and Latour JM
Cyclic peptides bearing a side-chain tail: A tool to model the structure and reactivity of protein zinc sites.
Angewandte Chemie International Edition, 2008, 47(36): 6888-6891

 

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